Breast cancer metastasis suppressor 1 (BRMS1) inhibits osteopontin transcription by abrogating NF-κB activation

BACKGROUND: Osteopontin (OPN), a secreted phosphoglycoprotein, has been strongly associated with tumor progression and aggressive cancers. MDA-MB-435 cells secrete very high levels of OPN. However metastasis-suppressed MDA-MB-435 cells, which were transfected with breast cancer metastasis suppressor...

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Main Authors: Samant, Rajeev S, Clark, David W, Fillmore, Rebecca A, Cicek, Muzaffer, Metge, Brandon J, Chandramouli, Kondethimmana H, Chambers, Ann F, Casey, Graham, Welch, Danny R, Shevde, Lalita A
格式: Artigo
語言:Inglês
出版: BioMed Central 2007
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1796551/
https://ncbi.nlm.nih.gov/pubmed/17227585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-6-6
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