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An improved genetic system for detection and analysis of protein nuclear import signals

BACKGROUND: Nuclear import of proteins is typically mediated by their physical interaction with soluble cytosolic receptor proteins via a nuclear localization signal (NLS). A simple genetic assay to detect active NLSs based on their function in the yeast Saccharomyces cerevisiae has been previously...

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Autors principals: Marshall, Kris S, Zhang, Zhiying, Curran, Jennifer, Derbyshire, Stephanie, Mymryk, Joe S
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1796550/
https://ncbi.nlm.nih.gov/pubmed/17254328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-8-6
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