Glutamate residues located within putative transmembrane helices are essential for TetA(P)-mediated tetracycline efflux.

The tetA(P) gene from Clostridium perfringens encodes a unique membrane protein that is responsible for the active efflux of tetracycline from resistant cells. The novel TetA(P) protein has neither the typical structure nor the conserved motifs that are found in tetracycline efflux proteins from cla...

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Bibliographic Details

Published in:	J Bacteriol
Main Authors:	Kennan, R M, McMurry, L M, Levy, S B, Rood, J I
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 1997
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC179641/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9371447/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.179.22.7011-7015.1997
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