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Development of B cells expressing surface immunoglobulin molecules that lack V(D)J-encoded determinants in the avian embryo bursa of Fabricius

Immunoglobulin gene rearrangement in avian B cell precursors generates surface Ig receptors of limited diversity. It has been proposed that specificities encoded by these receptors play a critical role in B lineage development by recognizing endogenous ligands within the bursa of Fabricius. To addre...

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Detalhes bibliográficos
Main Authors: Sayegh, Camil E., Demaries, Sandra L., Iacampo, Sandra, Ratcliffe, Michael J. H.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC17964/
https://ncbi.nlm.nih.gov/pubmed/10485907
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