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The acrAB homolog of Haemophilus influenzae codes for a functional multidrug efflux pump.

Disruption of gene HI0894 or HI0895 in Haemophilus influenzae Rd, homologs of Escherichia coli acrAB multidrug efflux genes, caused hypersusceptibility to erythromycin, rifampin, novobiocin, and dyes such as ethidium bromide and crystal violet and increased accumulation of radioactive erythromycin,...

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Bibliographic Details
Published in:J Bacteriol
Main Authors: Sánchez, L, Pan, W, Viñas, M, Nikaido, H
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1997
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC179619/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9352940/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.179.21.6855-6857.1997
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