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Chromatin remodeling directly activates V(D)J recombination

V(D)J recombination substrate choice is regulated to ensure that the appropriate gene segments are rearranged during lymphocyte development. It has been proposed that regulation of substrate usage is determined by changes in accessibility of the DNA targets. We show that Rag-mediated recombination o...

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Detalhes bibliográficos
Main Authors: Cherry, Sara R., Baltimore, David
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC17961/
https://ncbi.nlm.nih.gov/pubmed/10485904
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