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Chromatin remodeling directly activates V(D)J recombination

V(D)J recombination substrate choice is regulated to ensure that the appropriate gene segments are rearranged during lymphocyte development. It has been proposed that regulation of substrate usage is determined by changes in accessibility of the DNA targets. We show that Rag-mediated recombination o...

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Bibliografske podrobnosti
Main Authors: Cherry, Sara R., Baltimore, David
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 1999
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC17961/
https://ncbi.nlm.nih.gov/pubmed/10485904
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