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Alterations within the activation domain of the sigma 54-dependent activator DctD that prevent transcriptional activation.

Rhizobium meliloti DctD (C4-dicarboxylate transport protein D) is a transcriptional activator that catalyzes the ATP-dependent isomerization of closed complexes between sigma 54-RNA polymerase holoenzyme and the dctA promoter to open complexes. Following random mutagenesis of dctD, 55 independent mu...

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Bibliographic Details
Main Authors: Wang, Y K, Hoover, T R
Format: Artigo
Language:Inglês
Published: 1997
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC179471/
https://ncbi.nlm.nih.gov/pubmed/9294439
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