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Transition state heterogeneity in GCN4 coiled coil folding studied by using multisite mutations and crosslinking
We have investigated the folding behavior of dimeric and covalently crosslinked versions of the 33-residue α-helical GCN4-p1 coiled coil derived from the leucine zipper region of the transcriptional activator GCN4. The effects of multisite substitutions indicate that folding occurs along multiple ro...
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| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The National Academy of Sciences
1999
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC17946/ https://ncbi.nlm.nih.gov/pubmed/10485889 |
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