How complete are current yeast and human protein-interaction networks?

We estimate the full yeast protein-protein interaction network to contain 37,800-75,500 interactions and the human network 154,000-369,000, but owing to a high false-positive rate, current maps are roughly only 50% and 10% complete, respectively. Paradoxically, releasing raw, unfiltered assay data m...

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Hlavní autoři: Hart, G Traver, Ramani, Arun K, Marcotte, Edward M
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2006
Témata:
Opinion
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1794583/
https://ncbi.nlm.nih.gov/pubmed/17147767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2006-7-11-120
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