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Dynamic evolution of selenocysteine utilization in bacteria: a balance between selenoprotein loss and evolution of selenocysteine from redox active cysteine residues

BACKGROUND: Selenocysteine (Sec) is co-translationally inserted into protein in response to UGA codons. It occurs in oxidoreductase active sites and often is catalytically superior to cysteine (Cys). However, Sec is used very selectively in proteins and organisms. The wide distribution of Sec and it...

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Detalhes bibliográficos
Main Authors: Zhang, Yan, Romero, Hector, Salinas, Gustavo, Gladyshev, Vadim N
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1794560/
https://ncbi.nlm.nih.gov/pubmed/17054778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2006-7-10-r94
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