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Robustness Can Evolve Gradually in Complex Regulatory Gene Networks with Varying Topology

The topology of cellular circuits (the who-interacts-with-whom) is key to understand their robustness to both mutations and noise. The reason is that many biochemical parameters driving circuit behavior vary extensively and are thus not fine-tuned. Existing work in this area asks to what extent the...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Ciliberti, Stefano, Martin, Olivier C, Wagner, Andreas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1794322/
https://ncbi.nlm.nih.gov/pubmed/17274682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0030015
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