Lack of myostatin results in excessive muscle growth but impaired force generation

The lack of myostatin promotes growth of skeletal muscle, and blockade of its activity has been proposed as a treatment for various muscle-wasting disorders. Here, we have examined two independent mouse lines that harbor mutations in the myostatin gene, constitutive null (Mstn(−/−)) and compact (Ber...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Amthor, Helge, Macharia, Raymond, Navarrete, Roberto, Schuelke, Markus, Brown, Susan C., Otto, Anthony, Voit, Thomas, Muntoni, Francesco, Vrbóva, Gerta, Partridge, Terence, Zammit, Peter, Bunger, Lutz, Patel, Ketan
التنسيق: Artigo
اللغة:Inglês
منشور في: National Academy of Sciences 2007
الموضوعات:
Biological Sciences
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC1794294/
https://ncbi.nlm.nih.gov/pubmed/17267614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604893104
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