The Set1 Methyltransferase Opposes Ipl1 Aurora Kinase Functions in Chromosome Segregation

A balance in the activities of the Ipl1 Aurora kinase and the Glc7 phosphatase is essential for normal chromosome segregation in yeast. We report here that this balance is modulated by the Set1 methyltransferase. Deletion of SET1 suppresses chromosome loss in ipl1-2 cells. Conversely, combination of...

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Huvudupphovsmän: Zhang, Ke, Lin, Wenchu, Latham, John A., Riefler, Gary M., Schumacher, Jill M., Chan, Clarence, Tatchell, Kelly, Hawke, David H., Kobayashi, Ryuji, Dent, Sharon Y.R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2005
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1794220/
https://ncbi.nlm.nih.gov/pubmed/16143104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2005.06.021
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