The Set1 Methyltransferase Opposes Ipl1 Aurora Kinase Functions in Chromosome Segregation

A balance in the activities of the Ipl1 Aurora kinase and the Glc7 phosphatase is essential for normal chromosome segregation in yeast. We report here that this balance is modulated by the Set1 methyltransferase. Deletion of SET1 suppresses chromosome loss in ipl1-2 cells. Conversely, combination of...

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Main Authors: Zhang, Ke, Lin, Wenchu, Latham, John A., Riefler, Gary M., Schumacher, Jill M., Chan, Clarence, Tatchell, Kelly, Hawke, David H., Kobayashi, Ryuji, Dent, Sharon Y.R.
Format: Artigo
Sprog:Inglês
Udgivet: 2005
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1794220/
https://ncbi.nlm.nih.gov/pubmed/16143104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2005.06.021
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