The genes for butanol and acetone formation in Clostridium acetobutylicum ATCC 824 reside on a large plasmid whose loss leads to degeneration of the strain.

Degeneration is the process whereby Clostridium acetobutylicum ATCC 824 loses the capacity to produce acetone and butanol after repeated vegetative transfers or in continuous culture. Two degenerate mutants (M5 and DG1) of C. acetobutylicum ATCC 824 do not contain the four genes (ctfA, ctfB, adc, an...

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Pubblicato in:	J Bacteriol
Autori principali:	Cornillot, E, Nair, R V, Papoutsakis, E T, Soucaille, P
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC179415/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9286999/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.179.17.5442-5447.1997
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