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Emodin and DHA potently increase arsenic trioxide interferon-α–induced cell death of HTLV-I–transformed cells by generation of reactive oxygen species and inhibition of Akt and AP-1
Adult T-cell leukemia (ATL) is an aggressive lymphoproliferative disease of poor clinical prognosis associated with infection by the human T-cell leukemia virus type I (HTLV-I). The use of arsenic trioxide (As(2)O(3)) has been shown to effectively treat acute promyelocytic leukemia (APL) with greate...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society of Hematology
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1794054/ https://ncbi.nlm.nih.gov/pubmed/17077332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-04-015537 |
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