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Emodin and DHA potently increase arsenic trioxide interferon-α–induced cell death of HTLV-I–transformed cells by generation of reactive oxygen species and inhibition of Akt and AP-1

Adult T-cell leukemia (ATL) is an aggressive lymphoproliferative disease of poor clinical prognosis associated with infection by the human T-cell leukemia virus type I (HTLV-I). The use of arsenic trioxide (As(2)O(3)) has been shown to effectively treat acute promyelocytic leukemia (APL) with greate...

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Bibliografische gegevens
Hoofdauteurs: Brown, Megan, Bellon, Marcia, Nicot, Christophe
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2007
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1794054/
https://ncbi.nlm.nih.gov/pubmed/17077332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-04-015537
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