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Identification and characterization of an operon in Salmonella typhimurium involved in thiamine biosynthesis.

Thiamine pyrophosphate (TPP) is synthesized de novo in Salmonella typhimurium and is a required cofactor for many enzymes in the cell. Five kinase activities have been implicated in TPP synthesis, which involves joining a 4-methyl-5-(beta-hydroxyethyl)thiazole (THZ) moiety and a 4-amino-5-hydroxymet...

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Bibliographic Details
Main Authors: Petersen, L A, Downs, D M
Format: Artigo
Language:Inglês
Published: 1997
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC179339/
https://ncbi.nlm.nih.gov/pubmed/9244280
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