Role of the hemA gene product and delta-aminolevulinic acid in regulation of Escherichia coli heme synthesis.

We initiated these studies to help clarify the roles of heme, delta-aminolevulinic acid (ALA), hemA, and hemM in Escherichia coli heme synthesis. Using recombinant human hemoglobin (rHb1.1) as a tool for increasing E. coli's heme requirements, we demonstrated that heme is a feedback inhibitor of hem...

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Pubblicato in:	J Bacteriol
Autori principali:	Verderber, E, Lucast, L J, Van Dehy, J A, Cozart, P, Etter, J B, Best, E A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC179295/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9226269/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.179.14.4583-4590.1997
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