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Mck1, a member of the glycogen synthase kinase 3 family of protein kinases, is a negative regulator of pyruvate kinase in the yeast Saccharomyces cerevisiae.

An interaction between the Saccharomyces cerevisiae protein kinase Mck1 and pyruvate kinase (Pyk1) was detected by using the two-hybrid method. Purified Mck1 was able to phosphorylate purified Pyk1 on Ser in vitro. Pyruvate kinase activity was elevated in mck1 delta cells. Several of the phenotypes...

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Detalles Bibliográficos
Publicado en:J Bacteriol
Autores principales: Brazill, D T, Thorner, J, Martin, G S
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1997
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC179270/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9209064/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.179.13.4415-4418.1997
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