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Maximization of transcription of the serC (pdxF)-aroA multifunctional operon by antagonistic effects of the cyclic AMP (cAMP) receptor protein-cAMP complex and Lrp global regulators of Escherichia coli K-12.

The arrangement of the Escherichia coli serC (pdxF) and aroA genes into a cotranscribed multifunctional operon allows coregulation of two enzymes required for the biosynthesis of L-serine, pyridoxal 5'-phosphate, chorismate, and the aromatic amino acids and vitamins. RNase T2 protection assays revea...

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Bibliographic Details
Published in:J Bacteriol
Main Authors: Man, T K, Pease, A J, Winkler, M E
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1997
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC179136/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9171388/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.179.11.3458-3469.1997
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