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A Model for Antimicrobial Gene Therapy: Demonstration of Human β-Defensin 2 Antimicrobial Activities In Vivo
We transfected host cells with an antimicrobial peptide/protein-encoding gene as a way to enhance host defense mechanisms against infection. The human b-defensin 2 (HBD-2) gene was chosen as a model because its protein does not require cell type-specific processing. Using a retroviral vector carryin...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1790959/ https://ncbi.nlm.nih.gov/pubmed/12489997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/10430340260395875 |
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