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Regulation of heme biosynthesis in Salmonella typhimurium: activity of glutamyl-tRNA reductase (HemA) is greatly elevated during heme limitation by a mechanism which increases abundance of the protein.

In Salmonella typhimurium and Escherichia coli, the hemA gene encodes the enzyme glutamyl-tRNA reductase, which catalyzes the first committed step in heme biosynthesis. We report that when heme limitation is imposed on cultures of S. typhimurium, glutamyl-tRNA reductase (HemA) enzyme activity is inc...

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Detalles Bibliográficos
Publicado en:J Bacteriol
Autores principales: Wang, L Y, Brown, L, Elliott, M, Elliott, T
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1997
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC179053/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9139907/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.179.9.2907-2914.1997
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