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A mutation at proline-115 in the A-factor receptor protein of Streptomyces griseus abolishes DNA-binding ability but not ligand-binding ability.

A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) and its specific receptor protein (ArpA) are required for streptomycin production and aerial mycelium formation in Streptomyces griseus. A mutant strain HO1 that produced streptomycin and formed aerial mycelium and spores was derived fro...

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Vydáno v:J Bacteriol
Hlavní autoři: Onaka, H, Sugiyama, M, Horinouchi, S
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1997
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC179026/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9098075/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.179.8.2748-2752.1997
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