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Comparing the hypothalamic and extrahypothalamic actions of endogenous hyperleptinemia

To determine whether the depletion of body fat caused by adenovirus-induced hyperleptinemia is mediated via the hypothalamus, we used as a “bioassay” for hypothalamic leptin activity the hypothalamic expression of a leptin-regulated peptide, cocaine- and amphetamine-regulated transcript (CART). The...

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Autori principali: Wang, Zhuo-Wei, Zhou, Yan-Ting, Kakuma, Tetsuya, Lee, Young, Higa, Moritake, Kalra, Satya P., Dube, Michael G., Kalra, Pushpa S., Unger, Roger H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC17895/
https://ncbi.nlm.nih.gov/pubmed/10468615
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