A regulatory gene (ccaR) required for cephamycin and clavulanic acid production in Streptomyces clavuligerus: amplification results in overproduction of both beta-lactam compounds.

A regulatory gene (ccaR), located within the cephamycin gene cluster of Streptomyces clavuligerus, is linked to a gene (blp) encoding a protein similar to a beta-lactamase-inhibitory protein. Expression of ccaR is required for cephamycin and clavulanic acid biosynthesis in S. clavuligerus. The ccaR-...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Pérez-Llarena, F J, Liras, P, Rodríguez-García, A, Martín, J F
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1997
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC178932/
https://ncbi.nlm.nih.gov/pubmed/9068654
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