Mice lacking all conventional MHC class II genes

MHC class II (MHC-II) molecules play a central role in the selection of the T cell repertoire, in the establishment and regulation of the adaptive immune response, and in autoimmune deviation. We have generated knockout mice lacking all four of the classical murine MHC-II genes (MHCII(Δ)(/)(Δ) mice)...

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Detalhes bibliográficos
Main Authors: Madsen, Lars, Labrecque, Nathalie, Engberg, Jan, Dierich, Andrée, Svejgaard, Arne, Benoist, Christophe, Mathis, Diane, Fugger, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC17889/
https://ncbi.nlm.nih.gov/pubmed/10468609
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