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The HNF-4/HNF-1α transactivation cascade regulates gene activity and chromatin structure of the human serine protease inhibitor gene cluster at 14q32.1

Hepatocyte-specific expression of the α1-antitrypsin (α1AT) gene requires the activities of two liver-enriched transactivators, hepatocyte nuclear factors 1α and 4 (HNF-1α and HNF-4). The α1AT gene maps to a region of human chromosome 14q32.1 that includes a related serine protease inhibitor (serpin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Rollini, Pierre, Fournier, R. E. K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 1999
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC17884/
https://ncbi.nlm.nih.gov/pubmed/10468604
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