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Structure-function studies of the adenylate cyclase toxin of Bordetella pertussis and the leukotoxin of Pasteurella haemolytica by heterologous C protein activation and construction of hybrid proteins.

The adenylate cyclase toxin (CyaA) from Bordetella pertussis and the leukotoxin (LktA) from Pasteurella haemolytica are members of the RTX (stands for repeats in toxin) family of cytolytic toxins. They have pore-forming activity and share significant amino acid homology but show marked differences i...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Westrop, G, Hormozi, K, da Costa, N, Parton, R, Coote, J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC178772/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9006045/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.179.3.871-879.1997
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