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Role of transmembrane pH gradient and membrane binding in nisin pore formation.

Nisin is a cationic antimicrobial peptide that belongs to the group of lantibiotics. It is thought to form oligomeric pores in the target membrane by a mechanism that requires the transmembrane electrical potential delta psi and that involves local pertubation of the lipid bilayer structure. Here we...

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Published in:J Bacteriol
Main Authors: Moll, G N, Clark, J, Chan, W C, Bycroft, B W, Roberts, G C, Konings, W N, Driessen, A J
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1997
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC178671/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8981990/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.179.1.135-140.1997
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