Utilization of orotate as a pyrimidine source by Salmonella typhimurium and Escherichia coli requires the dicarboxylate transport protein encoded by dctA.

Mutants deficient in orotate utilization (initially termed out mutants) were isolated by selection for resistance to 5-fluoroorotate (FOA), and the mutations of 12 independently obtained isolates were found to map at 79 to 80 min on the Salmonella typhimurium chromosome. A gene complementing the mut...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Baker, K E, Ditullio, K P, Neuhard, J, Kelln, R A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC178620/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8955389/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.178.24.7099-7105.1996
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