GSTπ expression mediates dopaminergic neuron sensitivity in experimental parkinsonism

The cause of 95% of Parkinson's disease (PD) cases is unknown. It is hypothesized that PD arises from an interaction of free-radical-generating agents with an underlying genetic susceptibility to these compounds. Here we use the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of parkinsonism...

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Autors principals: Smeyne, Michelle, Boyd, Justin, Raviie Shepherd, Kennie, Jiao, Yun, Pond, Brooks Barnes, Hatler, Matthew, Wolf, Roland, Henderson, Colin, Smeyne, Richard Jay
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1785361/
https://ncbi.nlm.nih.gov/pubmed/17267597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610978104
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