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ISG15 modification of the eIF4E cognate 4EHP enhances cap structure-binding activity of 4EHP
The expression of the ubiquitin-like molecule ISG15 and protein modification by ISG15 (ISGylation) are strongly activated by interferon, genotoxic stress, and pathogen infection, suggesting that ISG15 plays an important role in innate immune responses. 4EHP is an mRNA 5′ cap structure-binding protei...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1785121/ https://ncbi.nlm.nih.gov/pubmed/17289916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1521607 |
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