The enhancement of pericentromeric cohesin association by conserved kinetochore components promotes high-fidelity chromosome segregation and is sensitive to microtubule-based tension

Sister chromatid cohesion, conferred by the evolutionarily conserved cohesin complex, is essential for proper chromosome segregation. Cohesin binds to discrete sites along chromosome arms, and is especially enriched surrounding centromeres, but past studies have not clearly defined the roles of arm...

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Bibliographic Details
Main Authors: Eckert, Carrie A., Gravdahl, Daniel J., Megee, Paul C.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2007
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1785119/
https://ncbi.nlm.nih.gov/pubmed/17242156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1498707
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