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The enhancement of pericentromeric cohesin association by conserved kinetochore components promotes high-fidelity chromosome segregation and is sensitive to microtubule-based tension

Sister chromatid cohesion, conferred by the evolutionarily conserved cohesin complex, is essential for proper chromosome segregation. Cohesin binds to discrete sites along chromosome arms, and is especially enriched surrounding centromeres, but past studies have not clearly defined the roles of arm...

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Autors principals: Eckert, Carrie A., Gravdahl, Daniel J., Megee, Paul C.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1785119/
https://ncbi.nlm.nih.gov/pubmed/17242156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1498707
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