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Towards abolition of immunogenic structures in insect cells: characterization of a honey-bee (Apis mellifera) multi-gene family reveals both an allergy-related core α1,3-fucosyltransferase and the first insect Lewis-histo-blood-group-related antigen-synthesizing enzyme

Glycoproteins from honey-bee (Apis mellifera), such as phospholipase A(2) and hyaluronidase, are well-known major bee-venom allergens. They carry N-linked oligosaccharide structures with two types of α1,3-fucosylation: the modification by α1,3-fucose of the innermost core GlcNAc, which constitutes a...

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Autors principals: Rendić, Dubravko, Klaudiny, Jaroslav, Stemmer, Ute, Schmidt, Julia, Paschinger, Katharina, Wilson, Iain B. H.
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783989/
https://ncbi.nlm.nih.gov/pubmed/17029591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060964
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