Regulation of the human mucin MUC4 by taurodeoxycholic and taurochenodeoxycholic bile acids in oesophageal cancer cells is mediated by hepatocyte nuclear factor 1α

MUC4 (mucin 4) is a membrane-bound mucin overexpressed in the early steps of oesophageal carcinogenesis and implicated in tumour progression. We previously showed that bile acids, main components of gastro-oesophageal reflux and tumour promoters, up-regulate MUC4 expression [Mariette, Perrais, Leteu...

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Hlavní autoři: Piessen, Guillaume, Jonckheere, Nicolas, Vincent, Audrey, Hémon, Brigitte, Ducourouble, Marie-Paule, Copin, Marie-Christine, Mariette, Christophe, Seuningen, Isabelle VAN
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2007
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783985/
https://ncbi.nlm.nih.gov/pubmed/17037983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061461
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