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An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation

The cardiac outflow tract develops as a result of a complex interplay among several cell types, including cardiac neural crest cells, endothelial cells, and cardiomyocytes. In both humans and mice, mutations in components of the Notch signaling pathway result in congenital heart disease characterize...

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Detalhes bibliográficos
Main Authors: High, Frances A., Zhang, Maozhen, Proweller, Aaron, Tu, LiLi, Parmacek, Michael S., Pear, Warren S., Epstein, Jonathan A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783803/
https://ncbi.nlm.nih.gov/pubmed/17273555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30070
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