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An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation

The cardiac outflow tract develops as a result of a complex interplay among several cell types, including cardiac neural crest cells, endothelial cells, and cardiomyocytes. In both humans and mice, mutations in components of the Notch signaling pathway result in congenital heart disease characterize...

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Autors principals: High, Frances A., Zhang, Maozhen, Proweller, Aaron, Tu, LiLi, Parmacek, Michael S., Pear, Warren S., Epstein, Jonathan A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783803/
https://ncbi.nlm.nih.gov/pubmed/17273555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30070
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