Endogenous ARF6 Interacts with Rac1 upon Angiotensin II Stimulation to Regulate Membrane Ruffling and Cell Migration

ARF6 and Rac1 are small GTPases known to regulate remodelling of the actin cytoskeleton. Here, we demonstrate that these monomeric G proteins are sequentially activated when HEK 293 cells expressing the angiotensin type 1 receptor (AT(1)R) are stimulated with angiotensin II (Ang II). After receptor...

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Main Authors: Cotton, Mathieu, Boulay, Pierre-Luc, Houndolo, Tanguy, Vitale, Nicolas, Pitcher, Julie A., Claing, Audrey
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2007
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783798/
https://ncbi.nlm.nih.gov/pubmed/17122362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-06-0567
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