N-WASP Involvement in Dorsal Ruffle Formation in Mouse Embryonic Fibroblasts

The Wiskott–Aldrich syndrome protein (WASP) family activates the Arp2/3 complex leading to the formation of new actin filaments. Here, we study the involvement of Scar1, Scar2, N-WASP, and Arp2/3 complex in dorsal ruffle formation in mouse embryonic fibroblasts (MEFs). Using platelet-derived growth...

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Hauptverfasser: Legg, John A., Bompard, Guillaume, Dawson, John, Morris, Hannah L., Andrew, Natalie, Cooper, Lisa, Johnston, Simon A., Tramountanis, Giorgos, Machesky, Laura M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2007
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783773/
https://ncbi.nlm.nih.gov/pubmed/17182853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-06-0569
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