POS5 Gene of Saccharomyces cerevisiae Encodes a Mitochondrial NADH Kinase Required for Stability of Mitochondrial DNA

In a search for nuclear genes that affect mutagenesis of mitochondrial DNA in Saccharomyces cerevisiae, an ATP-NAD (NADH) kinase, encoded by POS5, that functions exclusively in mitochondria was identified. The POS5 gene product was overproduced in Escherichia coli and purified without a mitochondria...

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Bibliographic Details
Main Authors: Strand, Micheline K., Stuart, Gregory R., Longley, Matthew J., Graziewicz, Maria A., Dominick, Olivia C., Copeland, William C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC178377/
https://ncbi.nlm.nih.gov/pubmed/12912900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.2.4.809-820.2003
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