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Molecular Ablation of Ventricular Tachycardia after Myocardial Infarction

Ventricular tachycardia is a common and lethal complication after myocardial infarction. Here, we show that focal gene transfer of KCNH2-G628S to the infarct scar border eliminated all ventricular arrhythmias in a porcine model. No proarrhythmia or other negative effects were discernable. Our result...

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Main Authors: Sasano, Tetsuo, McDonald, Amy D., Kikuchi, Kan, Donahue, J. Kevin
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783685/
https://ncbi.nlm.nih.gov/pubmed/17072309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1503
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