Assessment of Insulin Sensitivity in Adults with Permanent Neonatal Diabetes Mellitus due to Mutations in the KCNJ11 Gene Encoding Kir6.2

Activating mutations in the KCNJ11 gene encoding the Kir6.2 subunit of ATP-sensitive potassium channel have been described in patients with permanent neonatal diabetes mellitus (PNDM). The main pathophysiological feature of PNDM associated with Kir6.2 mutations is a profound defect in insulin secret...

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Autori principali: Skupien, Jan, Malecki, Maciej T., Mlynarski, Wojciech, Klupa, Tomasz, Wanic, Krzysztof, Gach, Agnieszka, Solecka, Iwona, Sieradzki, Jacek
Natura: Artigo
Lingua:Inglês
Pubblicazione: SBDR - Society for Biomedical Diabetes Research 2006
Soggetti:
Short Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783575/
https://ncbi.nlm.nih.gov/pubmed/17491708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1900/RDS.2006.3.17
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