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PSGL-1 and mTOR regulate translation of ROCK-1 and physiological functions of macrophages

Rho-associated kinases (ROCKs) are critical molecules involved in the physiological functions of macrophages, such as chemotaxis and phagocytosis. We demonstrate that macrophage adherence promotes rapid changes in physiological functions that depend on translational upregulation of preformed ROCK-1...

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Detalhes bibliográficos
Main Authors: Fox, Richard, Nhan, Thomas Q, Law, G Lynn, Morris, David R, Liles, W Conrad, Schwartz, Stephen M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783463/
https://ncbi.nlm.nih.gov/pubmed/17245434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601522
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