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COMMD1 promotes the ubiquitination of NF-κB subunits through a cullin-containing ubiquitin ligase
NF-κB is a pleiotropic transcription factor involved in multiple processes, including inflammation and oncogenesis. We have previously reported that COMMD1 represses κB-dependent transcription by negatively regulating NF-κB–chromatin interactions. Recently, ubiquitination of NF-κB subunits has been...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1783443/ https://ncbi.nlm.nih.gov/pubmed/17183367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601489 |
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