Baf60c is a nuclear Notch signaling component required for the establishment of left–right asymmetry

Notch-mediated induction of Nodal at the vertebrate node is a critical step in initiating left–right (LR) asymmetry. In mice and zebrafish we show that Baf60c, a subunit of the Swi/Snf-like BAF chromatin remodeling complex, is essential for establishment of LR asymmetry. Baf60c knockdown mouse embry...

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Détails bibliographiques
Auteurs principaux: Takeuchi, Jun K., Lickert, Heiko, Bisgrove, Brent W., Sun, Xin, Yamamoto, Masamichi, Chawengsaksophak, Kallayanee, Hamada, Hiroshi, Yost, H. Joseph, Rossant, Janet, Bruneau, Benoit G.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2007
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783402/
https://ncbi.nlm.nih.gov/pubmed/17210915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608118104
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