Interleukin-12 primes CD4(+) T cells for interferon-γ production and protective immunity during Mycobacterium avium infection

Interleukin-12 (IL-12) is a crucial cytokine for the generation of a protective immune response against Mycobacterium avium infection. In contrast to infected control mice, IL-12-deficient mice were unable to control bacterial proliferation and their spleen T cells were almost unresponsive in vitro...

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Autores principales: Silva, Regina A, Flórido, Manuela, Appelberg, Rui
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2001
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783245/
https://ncbi.nlm.nih.gov/pubmed/11454066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2001.01237.x
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