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Interleukin-12 primes CD4(+) T cells for interferon-γ production and protective immunity during Mycobacterium avium infection
Interleukin-12 (IL-12) is a crucial cytokine for the generation of a protective immune response against Mycobacterium avium infection. In contrast to infected control mice, IL-12-deficient mice were unable to control bacterial proliferation and their spleen T cells were almost unresponsive in vitro...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Blackwell Science Inc
2001
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1783245/ https://ncbi.nlm.nih.gov/pubmed/11454066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2001.01237.x |
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