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Mechanism and therapeutic potential of DNA-based immunization against the envelope proteins of hepatitis B virus in normal and transgenic mice

Two plasmid DNA vectors, pCAGGS(S) encoding the genes of the major envelope protein of hepatitis B virus (HBV), and pCAGGS(S + preS2) encoding the genes of the middle envelope protein were used to study the mechanism and therapeutic potential of DNA-based immunization. Injection of these plasmids in...

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Detalhes bibliográficos
Main Authors: OKA, YUICHIRO, FAZLE AKBAR, S M, HORIIKE, NORIO, JOKO, KOUJI, ONJI, MORIKAZU
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783213/
https://ncbi.nlm.nih.gov/pubmed/11380696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2001.01202.x
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