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Introducing endogenous antigens into the major histocompatibility complex (MHC) class II presentation pathway. Both Ii mediated inhibition and enhancement of endogenous peptide/MHC class II presentation require the same Ii domains

The invariant chain (Ii) plays a key role in regulating the antigen presentation function of major histocompatibility complex (MHC) class II molecules. Ii also influences the presentation of usually excluded endogenously synthesized proteins into the MHC class II presentation pathway. To evaluate th...

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Autori principali: Frauwirth, K, Shastri, N
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783207/
https://ncbi.nlm.nih.gov/pubmed/11328374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2001.01208.x
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