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Pentoxifylline treatment of mice with chronic pulmonary tuberculosis accelerates the development of destructive pathology

It is well established in animal models that production of the cytokine tumour necrosis factor-α (TNF-α) is essential to the proper expression of acquired specific resistance following infection with Mycobacterium tuberculosis. This gives rise to an apparent state of chronic disease which over the n...

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Autors principals: Turner, J, Frank, A A, Brooks, J V, Marietta, P M, Orme, I M
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783172/
https://ncbi.nlm.nih.gov/pubmed/11260331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2001.01161.x
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