Induction of a protective capsular polysaccharide antibody response to a multiepitope DNA vaccine encoding a peptide mimic of meningococcal serogroup C capsular polysaccharide

Systemic infection by encapsulated organisms, such as Neisseria meningitidis, is a major cause of morbidity and mortality worldwide, especially in individuals less than 2 years of age. Antibodies directed at the capsular polysaccharide are shown to be protective against disease by inducing complemen...

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Библиографические подробности
Главные авторы: Prinz, Deborah M, Smithson, S Louise, Kieber-Emmons, Thomas, Westerink, M A Julie
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Science Inc 2003
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Original Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783044/
https://ncbi.nlm.nih.gov/pubmed/14511238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2003.01732.x
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