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Limited role of charge matching in the interaction of human immunoglobulin A with the immunoglobulin A Fc receptor (FcαRI) CD89

Human immunoglobulin A (IgA) mediates protective effector mechanisms through interaction with specific cellular Fc receptors (FcαRI). Two IgA Fc interdomain loops (Leu257–Leu258 in the CH2 domain and Pro440–Phe443 in the CH3 domain) have previously been identified as critical for binding to FcαRI. O...

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Detalles Bibliográficos
Main Authors: Pleass, Richard J, Dehal, Prabhjyot K, Lewis, Melanie J, Woof, Jenny M
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782991/
https://ncbi.nlm.nih.gov/pubmed/12807477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2003.01677.x
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